Podstrona: Publications / Wizytówka pracownika PRz

1. Antos D., Kaczmarski K., Piątkowski W., „Chromatografia preparatywna jako proces rozdzielania mieszanin" (Preparative chromatography as a process for mixtures separating"), WNT, W-wa, 2014

   Chapters in monographies

   1. D. Antos, W. Piątkowski, “Kinetic and Thermodynamic Aspects of Hydrophobic Interaction Chromatography”, In book: „Advances in Chromatography”, vol. 59, 1-33, an imprint of Taylor & Francis Group, CRC Press, Boca Raton, USA, eBook ISBN 9781003330080, 2022. DOI: 10.1201/9781003330080-1

2. Antos, W. Piątkowski, (2024), “Equilibria and kinetics of ion-exchange of biopolymers”, Handbooks of Separation Science: “Ion-Exchange Chromatography and Related Techniques”, in book: “Ion-exchange chromatography and related techniques” , 1-st edition, Ch. 2, 25-49, edited by; P. Nesterenko, C. Poole, Y. Sun, Publisher Elsevier (S&T), Copyright © 2024 Elsevier Inc. eBook ISBN: 9780443153709, Paperback ISBN: 9780443153693

Articles 2023-2025

1. M. Olbrycht, J. Gumieniak, P. Mruc, M. Balawejder,W.  Piątkowski D. Antos., “Separation of non-racemic mixtures of enantiomers by achiral chromatography”, J. Chromatogr. A 1693 (2023) 46387,https://doi.org/10.1016/j.chroma.2023.463877
2. R. Muca, D. Antos, “Protein association on multimodal chromatography media”, J. Chromatogr. A, 1691 (2023) 46382, https://doi: 10.1016/j.chroma.2023.463827
3. P.. Zimoch, T. Rumanek, M.  Kołodziej, W. Piątkowski D. Antos, "Coupling of chromatography and precipitation for adjusting acidic variant content in a monoclonal antibody pool", J. Chromatogr. A 1701 (2023) 46407. https://doi.org/10.1016/j.chroma.2023.464070
4. B. Filip, R. Bochenek, W. K. Marek, D. Antos, "Flow behavior of protein solutions in a lab-scale chromatographic system", J. Chromatogr. A 1705 (2023) 46417. https://doi.org/10.1016/j.chroma.2023.464178
5. P. Mruc, M. Olbrycht, M. Korbetskyy, . Antos," Altering the mobile phase composition to enhance self-disproportionation of enantiomers in achiral chromatography", J. Chromatogr. A 1715 (2024) 464603,  https://doi.org/10.1016/j.chroma.2023.464603
6. T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, ”Countercurrent preferential precipitation of acidic variants from monoclonal antibody pools”, Chem. Eng. Res. Des. (CHERD), 202 (2024) 336–345,https://doi.org/10.1016/j.cherd.2024.01.001

7. T.Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Isolation and purification of a monoclonal antibody from a cell culture supernatant by multistage precipitation and solid-liquid extraction”, Food Bioprod. Process. 147 (2024) 34-41,https://doi.org/10.1016/j.fbp.2024.05.016

8. I. Poplewska, B. Strachota, A. Strachota, G. Poplewski, D.  Antos, “Thermo- and pH-Responsible Gels for Efficient Protein Adsorption and Desorption”, Molecules 29 (2024) 4858, https://doi.org/10.3390/molecules29204858
9. B. Filip, M. Kołodziej, R. Bochenek, M. Chutkowski, D. Antos, “Computational Fluid Dynamics for Determining the Interplay between Stirring Conditions and Crystal Size Distribution in Small Laboratory Devices”, Ind. Eng. Chem. Res. 63 (2024) 16208−16219, https://doi.org/10.1021/acs.iecr.4c01816
10. P. Zimoch-Rumanek, D. Antos, “Coupling cation and anion exchange chromatography for fast separation of monoclonal antibody charge variants”. J. Chromatogr. A,  1733 (2024) 465256,https://doi.org/10.1016/j.chroma.2024.465256
11. T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Countercurrent preferential precipitation of acidic variants from monoclonal antibody pools”, Chem. Eng. Res. Des. 202 (2024) 336–345, https://doi.org/10.1016/j.cherd.2024.01.001
12. D. Antos, R. Muca, “Interplay between the isotherm course and the efficiency of mAb purification in flowthrough and bind-and-elute modes on cation exchange resins”, ”. J. Chromatogr. A, 1743 (2025) 465682, https://doi: 10.1016/j.chroma.2025.465682
13. W.K. Marek, J.W. Lee, A. Seidel-Morgenstern, D. Antos, “Separation of nonracemic mixtures of enantiomers by achiral simulated moving bed chromatography”, Sep. Purif. Technol., 361, 131497, https://doi:10.1016/j.seppur.2025.131497
14. P. Mruc, D. Antos,  “Coupling Achiral and Chiral Chromatography for Efficient Separation of Enantiomeric Mixtures”, Ind. Eng. Chem. Res. 2025, 64, 7826−7837, https://doi.org/10.1021/acs.iecr.5c00412
15. M. Kołodziej, I. Poplewska, D. Antos, “From harvest to crystalline product form: A combination of crystallization with non-chromatography pre-purification steps for monoclonal antibody capture, purification, and formulation”, Sep. Purif. Technol., (2025),  372 (2025), 133478, https://doi.org/10.1016/ j.seppur.2025.133478

Contribution to the conferences and symposiums 2022-2024

1. P. Zimoch, T. Rumanek, K. Baran, M. Kołodziej, W. Piątkowski, D. Antos^, „Coupling preferential precipitation and iex for reducing acidic variant content in monoclonal antibody pools”, PREP 2022 (35^th), Baltimore, USA, L-305.
2. M. Olbrycht, J. Gumieniak, P. Sroka, W. Piątkowski, D. Antos, „Separation of Non-Racemic Mixtures of Enantiomers by Achiral Chromatography”, PREP 2022 (35^th), Baltimore, USA, P-T-103.
3. I. Poplewska, P. Zimoch, D. Antos, „pH excursion during processing of monoclonal antibodies on strong cation exchange resins”, PREP 2022 (35^th), Baltimore, USA,
   P-M-104.
4. P. Zimoch, T. Rumanek, M. Kolodziej, W. Piątkowski, D. Antos, “Coupling preferential precipitation and IEX for reducing acidic variant content in monoclonal antibody pools”, SPICA 2022, Lisbon, Portugal 11-14, 10, 2022. OC04 | P45.
5. M. Olbrycht, J. Gumieniak, P. Sroka, W. Piątkowski, D. Antos, „Separation of non-racemic mixtures of enantiomers by achiral chromatography”, SPICA 2022, Lisbon, Portugal 11-14, 10, 2022.
6. P. Zimoch, T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Coupling preferential precipitation and IEX for reducing acidic variant content in monoclonal antibody pools”, SPICA 2022, Lisbon, Portugal 11-14, 10, 2022., P45.
7. D. Antos, T. Rumanek, M. Kołodziej, P. Zimoch, W. Piątkowski, „PEG-aided precipitation for adjusting acidic variant content in a monoclonal antibody pool”, ISPPP 2023 Vienna, Austria, OP17 (L), invited L
8. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, „Separation of non-racemic mixtures of enantiomers by achiral chromatography”, PREP 2024 (36^th), Philadelphia, USA, P002.
9. W. K. Marek, J.W.L., A. Seidel-Morgenstern, D. Antos “Continuous separation of enantiomers in SMB chromatography with achiral stationary phase”, PREP 2024 (36^th), Philadelphia, USA, L.
10. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, “Altering the operating conditions to enhance self-disproportionation of enantiomers in achiral chromatography”, 19th SPICA 2024, P35.
11. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, “Separation of non-racemic mixtures of enantiomers by achiral chromatography”, 19th, SPICA 2024, L, OC04.
12. W.K. Marek, J.W.L., A. Seidel-Morgenstern, D. Antos “Continuous separation of enantiomers in SMB chromatography with achiral stationary phase”, Lecture 19th SPICA 2024, P34.
13. M. Korbetskyy, M. Olbrycht, D. Antos, “Temperature-mediated switch of the phase behavior to separate enantiomers of methyl p-tolyl sulfoxide”, 8th EU CONF. ON CRYSTAL GROWTH, Warsaw, 21-25 July 2024, P.
14. M. Kołodziej, B. Filip, R. Bochenek, M. Chutkowski, D. Antos, “Computational Fluid Dynamics for determining the interplay between stirring technique and crystal size distribution”, 8th EU CONF. ON CRYSTAL GROWTH, Warsaw, 21-25 July 2024, P.

1. M. Olbrycht, J. Gumieniak, P. Mruc, W. Piątkowski, D. Antos, “Separation modeling of non-racemic mixtures of enantiomers by achiral chromatography”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P. 
2. T. Rumanek, P. Zimoch, M. Kołodziej, W. Piątkowski, D. Antos, “Separation of monoclonal antibody charge variants by peg-aided precipitation and IEX chromatography”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P.
3. P. Mruc, M. Olbrycht, D. Antos, “Influence of mobile phase on separation of enantiomers of methyl p-tolyl sulfoxide”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P.
4. B. Filip, R. Bochenek, D. Antos, “Determination of fluid phase behaviour in liquid chromatography with CFD method”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, L S5.

Grants

1. Supervisor of the NCN grant OPUS UMO-2021/41/B/ST8/00631 for a research project UMO-2021/41/B/ST8/00631, “Separation of enantiomeric mixtures of pharmaceutically active substances using hybrid processes of achiral and chiral chromatography and achiral crystallization” („Rozdzielanie mieszanin enencjomerów substancji farmaceutycznie czynnych z wykorzystaniem hybrydowych procesów chromatografii achiralnej i chiralnej oraz achiralnej krystalizacji”) 2021-2025
2. Supervisor of the NCN grant OPUS_LAP UMO-2023/51/I/ST8/01518 for the research project, “Continuous protein crystallization” (“Ciągła krystalizacja białek”) 2024-2027

Patents 2020-2024

1. M. Olbrycht. D. Antos, W. Piątkowski, A. Bajek-Bil, M. Balawejder, „Method for obtaining the stereoisomer of naphronyl oxalate with absolute configuration (2S,2’R)”,  pat. No P.425655 [WIPO ST 10/C PL425655]. Date of granting the patent: 2020-09-01.
2. D. Antos, R. Bochenek, M. Kołodziej, M. Olbrycht. W. Piątkowski, M. Przywara, "Method for producing multi-component fertilizer with controlled release of components" P. 429318 [WIPO ST 10/C PL429318]  Date of granting the patent: 2020-20-10.
3. D. Antos, W. Piątkowski, M. Kołodziej, T. Rumanek, P. Zimoch, "Method for separating variants of monoclonal antibodies", P. 441857 [WIPO ST 10/C PL429318] date: 2022-07-27.
4. D. Antos, W. Piątkowski, M. Kołodziej, T. Rumanek, "Method for separating variants of monoclonal antibodies","P.448410 [WIPO ST 10/C PL448410] date:2024-04-25.