Podstrona: Publikacje / Wizytówka pracownika PRz

1. Antos D., Kaczmarski K., Piątkowski W., „Chromatografia preparatywna jako proces rozdzielania mieszanin”,,  WNT, W-wa 2011, wyd..2 zmienione WNT, W-wa 2014

1. Olbrycht, J. Gumieniak, P. Mruc, M. Balawejder,W.  Piątkowski D. Antos., “Separation of non-racemic mixtures of enantiomers by achiral chromatography”, J. Chromatogr. A 1693 (2023) 46387,https://doi.org/10.1016/j.chroma.2023.463877

2. R. Muca, D. Antos, “Protein association on multimodal chromatography media”, J. Chromatogr. A, 1691 (2023) 46382, https://doi: 10.1016/j.chroma.2023.463827
3. P. Zimoch, T. Rumanek, M.  Kołodziej, W. Piątkowski D. Antos, "Coupling of chromatography and precipitation for adjusting acidic variant content in a monoclonal antibody pool", J. Chromatogr. A 1701 (2023) 46407. https://doi.org/10.1016/j.chroma.2023.464070
4. B. Filip, R. Bochenek, W. K. Marek, D. Antos, "Flow behavior of protein solutions in a lab-scale chromatographic system", J. Chromatogr. A 1705 (2023) 46417. https://doi.org/10.1016/j.chroma.2023.464178
5. P. Mruc, M. Olbrycht, M. Korbetskyy, . Antos," Altering the mobile phase composition to enhance self-disproportionation of enantiomers in achiral chromatography", J. Chromatogr. A 1715 (2024) 464603,  https://doi.org/10.1016/j.chroma.2023.464603

6. T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, ”Countercurrent preferential precipitation of acidic variants from monoclonal antibody pools”, Chem. Eng. Res. Des. (CHERD), 202 (2024) 336–345,https://doi.org/10.1016/j.cherd.2024.01.001

7. T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Isolation and purification of a monoclonal antibody from a cell culture supernatant by multistage precipitation and solid-liquid extraction”, Food Bioprod. Process. 147 (2024) 34-41, https://doi.org/10.1016/j.fbp.2024.05.016

8. I. Poplewska, B. Strachota, A. Strachota, G. Poplewski, D.  Antos, “Thermo- and pH-Responsible Gels for Efficient Protein Adsorption and Desorption”, Molecules 29 (2024) 4858, https://doi.org/10.3390/molecules29204858
9. B. Filip, M. Kołodziej, R. Bochenek, M. Chutkowski, D. Antos, “Computational Fluid Dynamics for Determining the Interplay between Stirring Conditions and Crystal Size Distribution in Small Laboratory Devices”, Ind. Eng. Chem. Res. 63 (2024) 16208−16219, https://doi.org/10.1021/acs.iecr.4c01816
10. Zimoch-Rumanek, D. Antos, “Coupling cation and anion exchange chromatography for fast separation of monoclonal antibody charge variants”. J. Chromatogr. A,  1733 (2024) 465256,https://doi.org/10.1016/j.chroma.2024.465256

11. T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Countercurrent preferential precipitation of acidic variants from monoclonal antibody pools”, Chem. Eng. Res. Des. 202 (2024) 336–345, https://doi.org/10.1016/j.cherd.2024.01.001
12. D. Antos, R. Muca, “Interplay between the isotherm course and the efficiency of mAb purification in flowthrough and bind-and-elute modes on cation exchange resins”, ”. J. Chromatogr. A, 1743 (2025) 465682 https://doi: 10.1016/j.chroma.2025.465682
13. K. Marek, J.W. Lee, A. Seidel-Morgenstern, D. Antos, “Separation of nonracemic mixtures of enantiomers by achiral simulated moving bed chromatography”, Sep. Purif. Technol., 361, 131497, https://doi:10.1016/j.seppur.2025.131497
14. P. Mruc, D. Antos, Cite “Coupling Achiral and Chiral Chromatography for Efficient Separation of Enantiomeric Mixtures”, Ind. Eng. Chem. Res. 2025, 64, 7826−7837, M. https://doi.org/10.1021/acs.iecr.5c00412

15. M. Kołodziej, I. Poplewska, D. Antos, “From harvest to crystalline product form: A combination of crystallization with non-chromatography pre-purification steps for monoclonal antibody capture, purification, and formulation”, Sep. Purif. Technol., (2025), 372 (2025), 133478, https://doi.org/10.1016/ j.seppur.2025.133478

Udział czynny w konferencjach i sympozjach 2022-2024

1. P. Zimoch, T. Rumanek, K. Baran, M. Kołodziej, W. Piątkowski, D. Antos^, „Coupling preferential precipitation and iex for reducing acidic variant content in monoclonal antibody pools”, PREP 2022 (35^th), Baltimore, USA, L-305.
2. M. Olbrycht, J. Gumieniak, P. Sroka, W. Piątkowski, D. Antos, „Separation of Non-Racemic Mixtures of Enantiomers by Achiral Chromatography”, PREP 2022 (35^th), Baltimore, USA, P-T-103.
3. I. Poplewska, P. Zimoch, D. Antos, „pH excursion during processing of monoclonal antibodies on strong cation exchange resins”, PREP 2022 (35^th), Baltimore, USA,
   P-M-104.
4. P. Zimoch, T. Rumanek, M. Kolodziej, W. Piątkowski, D. Antos, “Coupling preferential precipitation and IEX for reducing acidic variant content in monoclonal antibody pools”, SPICA 2022, Lisbon, Portugal, OC04 | P45.
5. M. Olbrycht, J. Gumieniak, P. Sroka, W. Piątkowski, D. Antos, „Separation of non-racemic mixtures of enantiomers by achiral chromatography”, SPICA 2022, Lisbon, Portugal, P19.
6. P. Zimoch, T. Rumanek, M. Kołodziej, W. Piątkowski, D. Antos, “Coupling preferential precipitation and IEX for reducing acidic variant content in monoclonal antibody pools”, SPICA 2022, Lisbon, Portugal, P45.
7. D. Antos, T. Rumanek, M. Kołodziej, P. Zimoch, W. Piątkowski, „PEG-aided precipitation for adjusting acidic variant content in a monoclonal antibody pool”, ISPPP 2023 Vienna, Austria, OP17 (L), invited L.
8. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, „Separation of non-racemic mixtures of enantiomers by achiral chromatography”, PREP 2024 (36^th), Philadelphia, USA, P002.
9. W. K. Marek, J.W.L., A. Seidel-Morgenstern, D. Antos “Continuous separation of enantiomers in SMB chromatography with achiral stationary phase”, PREP 2024 (36^th), Philadelphia, USA, L.
10. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, “Altering the operating conditions to enhance self-disproportionation of enantiomers in achiral chromatography”, 19th SPICA 2024, P35.
11. M. Olbrycht, P. Mruc, J. Gumieniak, W. Piątkowski, D. Antos, “Separation of non-racemic mixtures of enantiomers by achiral chromatography”, 19th, SPICA 2024, L, OC04.
12. W. K. Marek, J.W.L., A. Seidel-Morgenstern, D. Antos “Continuous separation of enantiomers in SMB chromatography with achiral stationary phase”, Lecture 19th SPICA 2024, P34.
13. M. Korbetskyy, M. Olbrycht, D. Antos, “Temperature-mediated switch of the phase behavior to separate enantiomers of methyl p-tolyl sulfoxide”, 8th EUROPEAN CONFERENCE ON CRYSTAL GROWTH, Warsaw, 21-25 July 2024, P, str. 35.
14. M. Kołodziej, B. Filip, R. Bochenek, M. Chutkowski, D. Antos, “Computational Fluid Dynamics for determining the interplay between stirring technique and crystal size distribution”, 8th EUROPEAN CONFERENCE ON CRYSTAL GROWTH, Warsaw, 21-25 July 2024, P, str. 6.

1. M. Olbrycht, J. Gumieniak, P. Mruc, W. Piątkowski, D. Antos, “Separation modeling of non-racemic mixtures of enantiomers by achiral chromatography”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P str. 359. 
2. T. Rumanek, P. Zimoch, M. Kołodziej, W. Piątkowski, D. Antos, “Separation of monoclonal antibody charge variants by peg-aided precipitation and IEX chromatography”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P str. 264.
3. P. Mruc, M. Olbrycht, D. Antos, “Influence of mobile phase on separation of enantiomers of methyl p-tolyl sulfoxide”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, P str. 342.
4. B. Filip, R. Bochenek, D. Antos, “Determination of fluid phase behaviour in liquid chromatography with CFD method”, 24th PCC&PE (Polish Conference of Chemical and Process Engineering), 13–16 June 2023, Szczecin, Poland, L S5 str. 98.

GRANTY

1. Kierownik grantu NCN OPUS UMO-2021/41/B/ST8/00631 (UMO-2021/41/B/ST8/00631), "Rozdzielanie mieszanin enancjomerów substancji farmaceutycznie czynnych z wykorzystaniem hybrydowych procesów chromatografii achiralnej i chiralnej oraz achiralnej krystalizacji", 2021-2025
2. Kierownik grantu NCN OPUS_LAP UMO-2023/51/I/ST8/01518 na realizację projektu badawczego „Ciągła krystalizacja białek” 2024-2027

PATENTY 2020-2024

1. M. Olbrycht. D. Antos, W. Piątkowski, A. Bajek-Bil, M. Balawejder, „Sposób otrzymywania stereoizomeru szczawianu nafronylu o konfiguracji absolutnej (2S,2’R)”, zgł. pat. Nr P.425655 [WIPO ST 10/C PL425655] z dnia 11.06.2018. Data udzielenia patentu: 2020-09-01.
2. D. Antos, R. Bochenek, M. Kołodziej, M. Olbrycht. W. Piątkowski, M. Przywara, „Sposób wytwarzania nawozu wieloskładnikowego o kontrolowanym uwalnianiu składników’, P. 429318 [WIPO ST 10/C PL429318] z dnia 22.03.2019. Data udzielenia patentu: 2020-20-10.
3. D. Antos, W. Piątkowski, M. Kołodziej, T. Rumanek, P. Zimoch, „Sposób rozdzielania wariantów przeciwciał monoklonalnych”, P. 441857 [WIPO ST 10/C PL429318] z dnia 2022-07-27.
4. D. Antos, W. Piątkowski, M. Kołodziej, T. Rumanek, „Sposób izolacji przeciwciał monoklonalnych z mieszaniny pohodowlanej”, P.448410 [WIPO ST 10/C PL448410] z dnia 2024-04-25.